Horizontal Scrolling

Came across this article on Smashing Magazine, it got me thinking.

How many internet users use a scrolling mouse, and actually use the scroll wheel?

It looks potentially like a really nice alternate way of presenting a website. Perhaps using it, with changes in the pipeline for CSS, would enable us to create horizontal-read columns a la magazine or newspaper. But a few tricks will have to be found with the behaviour of 'height:' and 'width:' otherwise smaller screens will vertically scroll, and larger screens will have lots of empty space (try this).

Certainly got me thinking of new possibilities for the web... :)